Type 3 disease

The severity of type 3 disease (chronic neuronopathic) is usually regarded as between that of types 1 and 2, although less severe forms of type 3 disease also exist. As well as a range of symptoms and signs associated with type 1 disease, type 3 includes neurological involvement  (with a later onset and relatively lesser severity then in type 2): Grabowski GA, Petsko GA, Kolodny EH. Chapter 146: Gaucher disease. Valle D, Beaudet AL, Vogelstein B, et al, eds. The Online Metabolic and Molecular Bases of Inherited Disease. New York, NY: McGraw Hill; 2013. Accessed July 6, 2015.

  • supranuclear gaze palsy
  • ataxia.